Cardiology CPT Codes in 2025

Medical coding moves fast—especially in cardiology, where accurate coding is everything. The smallest update in a CPT code can mean the difference between a smooth claim approval and a never-ending back-and-forth with insurers.

This isn’t just another list of changes. This is your shortcut to what actually matters in 2025:
✅ CPT codes shaping the future of cardiology billing
✅ Key updates that fine-tune accuracy and reimbursement
✅ Hidden shifts that make coding easier—if you know where to look

If you’re in medical coding, cardiology billing, or revenue cycle management, this isn’t optional reading—it’s your edge in staying ahead.

No fluff. No filler. Just exactly what you need to know. Let’s get straight to it. 

The Core Categories of Cardiology CPT Codes in 2025

To make it easier to understand, we’ve broken down cardiology CPT codes into five core categories, each covering a distinct aspect of heart-related procedures. Whether it’s diagnostic imaging, pediatric interventions, consults, or interventional cardiology, this section will give you a comprehensive yet streamlined look at the most relevant CPT codes for 2025.

Nuclear Cardiology CPT Codes

Nuclear cardiology involves using radioactive substances to visualize the heart's structure and function. Key CPT codes include:

1. Myocardial Perfusion Imaging (MPI):

• 78451: Myocardial perfusion imaging, tomographic (SPECT); single study, at rest or stress (exercise or pharmacologic).​

• 78452: Myocardial perfusion imaging, tomographic (SPECT); multiple studies, at rest and/or stress (exercise and/or pharmacologic).​

2. Cardiac Blood Pool Imaging:

• 78472: Cardiac blood pool imaging, gated equilibrium; planar, single study at rest or stress.​

• 78473: Cardiac blood pool imaging, gated equilibrium; multiple studies, wall motion plus ejection fraction, at rest and stress.​

• 78494: Cardiac blood pool imaging, gated equilibrium, SPECT.​

3. Metabolic Evaluation:

• 78459: Myocardial imaging, positron emission tomography (PET), metabolic evaluation.​

4. Infarct Imaging:

• 78466: Myocardial imaging, infarct avid, planar; single study.​

• 78468: Myocardial imaging, infarct avid, planar; multiple studies.​

• 78469: Myocardial imaging, infarct avid, tomographic (SPECT).​

5. Vascular Flow Imaging:

• 78445: Venous thrombosis imaging, radionuclide study.​

6. Non-Specific Codes:

• 78499: Unlisted cardiovascular procedure, diagnostic nuclear medicine

Pediatric Cardiology CPT Codes

Pediatric cardiology addresses heart conditions in children. Notable CPT codes include

• 93303: Transthoracic echocardiography for congenital cardiac anomalies; complete.​

• 93304: Transthoracic echocardiography for congenital cardiac anomalies; follow-up or limited study.​

• 93531: Combined right heart catheterization and transseptal left heart catheterization.

CPT Codes for Cardiology Consult 

Cardiology consultations require precise coding to reflect the services provided. Key CPT codes include:

• 99242: Office consultation for a new or established patient, typically 30 minutes.​

• 99243: Office consultation for a new or established patient, typically 40 minutes.​

• 99244: Office consultation for a new or established patient, typically 60 minutes.

Most Common Cardiology CPT Codes 

• 93000: Electrocardiogram, routine ECG with at least 12 leads; with interpretation and report.

• 93010: Electrocardiogram, routine ECG with at least 12 leads; interpretation and report only.

• 93306: Echocardiography, transthoracic, real-time with image documentation (2D), includes M-mode recording, complete, with spectral and color Doppler.

• 93015: Cardiovascular stress test using maximal or submaximal treadmill or bicycle exercise, continuous electrocardiographic monitoring, and/or pharmacological stress; with supervision, interpretation, and report.​

Interventional Cardiology CPT Codes

Percutaneous Coronary Intervention (PCI) Codes

These cover angioplasty, stent placement, and atherectomy.

• 92920 – Percutaneous transluminal coronary angioplasty (PTCA), single major coronary artery or branch

• 92921 – PTCA, each additional branch (add-on code)

• 92924 – Percutaneous transluminal coronary atherectomy, with or without angioplasty, single major coronary artery or branch

• 92925 – Atherectomy, each additional branch (add-on code)

• 92928 – Percutaneous transcatheter placement of intracoronary stent(s), with angioplasty if performed, single major coronary artery or branch

• 92929 – Stent placement, each additional branch (add-on code)

• 92933 – Percutaneous transluminal coronary atherectomy + intracoronary stent, with angioplasty if performed, single major coronary artery or branch

• 92934 – Atherectomy + Stent, each additional branch (add-on code)

Medicare and private payers now require precise documentation of which vessel was treated using artery modifiers:

• LD – Left anterior descending artery

• RC – Right coronary artery

• LC – Left circumflex artery

Coronary Thrombectomy & Additional Procedures

These codes represent adjunct therapies performed alongside PCI:

• 92973 – Percutaneous thrombectomy (coronary) during PCI (add-on code)

• 92978 – Intravascular ultrasound (IVUS), coronary or grafts, initial vessel

• 92979 – IVUS, each additional vessel (add-on code)

Fractional Flow Reserve (FFR) & Optical Coherence Tomography (OCT)

FFR and OCT help assess lesion severity and guide stent placement.

• 93571 – FFR, initial vessel (add-on code)

• 93572 – FFR, each additional vessel (add-on code)

• 92929 – OCT, initial vessel

• 92930 – OCT, each additional vessel

Chronic Total Occlusion (CTO) Intervention

CTO procedures involve treating completely blocked arteries.

• 92943 – CTO percutaneous intervention, single major artery

• 92944 – CTO intervention, each additional artery

Words By Author

Cardiology CPT codes play a crucial role in bridging clinical expertise with reimbursement standards. To optimize billing practices, practitioners must have a deep understanding of cardiology procedures while staying updated on evolving reimbursement policies. Precision in documentation, strategic coding, and regulatory compliance are essential for financial sustainability and excellence in cardiology care.

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